The Washington State University Catalog

Courses with the MBIOS Subject

The online catalog includes the most recent changes to courses and degree requirements that have been approved by the Faculty Senate, including changes that are not yet effective. Courses showing two entries of the same number indicate that the course information is changing. The most recently approved version is shown first, followed by the older version, in gray, with its last-effective term preceding the course title. Courses shown in gray with only one entry of the course number are being discontinued.

Courses

Molecular Biosciences (MBIOS)

101 [BSCI] Introductory Microbiology 4 (3-3) Course Prerequisite: Not intended for majors in the School of Molecular Biosciences. Microbiology for the informed citizen as it impacts humans and their environment. Not for students needing BIOLOGY 106 and 107. Typically offered Fall, Spring, and Summer.

138 Molecular Biosciences Seminar 1 Introduction to the field of molecular biosciences: careers, current events, research opportunities at WSU, scientific and research ethics. Typically offered Spring. S, F grading.

201 [COMM] Introduction to Communication in the Molecular Life Sciences 3 (1-4) Course Prerequisite: BIOLOGY 106 with a C or better or BIOLOGY 107 with a C or better. Analysis of primary literature and an introduction to scientific communication skills in the molecular life sciences. (Crosslisted course offered as NEUROSCI 201, MBIOS 201). Recommended preparation: Pre-certified or certified major in Biochemistry, Genetics & Cell Biology, Microbiology, or Neuroscience. Typically offered Spring.

210 Your Future in Life Sciences 2 Exploration of career options in biological sciences with faculty and outside speakers; guide to preparing resume and career plans. (Crosslisted course offered as SCIENCE 210, BIOLOGY 210, MBIOS 210). Typically offered Fall. S, F grading.

301 General Genetics 4 Course Prerequisite: BIOLOGY 106 or 120; BIOLOGY 107; CHEM 101 or 105; CHEM 102 or 106. Principles of modern and classical genetics. (Crosslisted course offered as MBIOS 301, BIOLOGY 301). Typically offered Fall, Spring, and Summer.

303 Introductory Biochemistry 4 Course Prerequisite: CHEM 102 or 345. Modern biochemistry for undergraduates in the biological sciences. Typically offered Fall, Spring, and Summer. Cooperative: Open to UI degree-seeking students.

304 Microbiology and Molecular Biology Laboratory 3 (1-6) Course Prerequisite: MBIOS 303 or concurrent enrollment, or MBIOS 305 or concurrent enrollment. Basic microbiology and molecular biology techniques. Typically offered Fall, Spring, and Summer.

305 General Microbiology 3 Course Prerequisite: BIOLOGY 107; CHEM 102 or 345. Structure, function, nutrition, physiology, and genetics of microbes and their application to immunology, pathology, microbial diversity, and environmental microbiology. Recommended preparation: MBIOS 303. Typically offered Fall, Spring, and Summer.

306 General Microbiology Laboratory 2 (0-6) Course Prerequisite: MBIOS 305 or concurrent enrollment. Laboratory for MBIOS 305.

320 [BSCI] DNA and Society 3 The role of DNA in natural processes and diseases; impact of biotechnology on health care, agriculture, industry, and our lives. Recommended preparation: One college-level course in biology highly recommended. Typically offered Fall and Spring.

342 Microbial Ecology 3 Course Prerequisite: BIOLOGY 106 or 120; CHEM 102 or concurrent enrollment, or CHEM 345 or concurrent enrollment. Discussion of microorganism behavior in nature and microbial activities influence on ecological balance. Typically offered Fall.

360 [M] Cell and Molecular Laboratory 2 (0-6) Course Prerequisite: MBIOS 301; MBIOS 303 or concurrent enrollment. Laboratory methods in cell biology, genetics and molecular biology. Typically offered Spring.

401 Cell Biology 3 Course Prerequisite: MBIOS 301; MBIOS 303 or concurrent enrollment. Cellular structure and function; membrane biochemistry and transport; cell-cell communication; regulation of cell cycle and apoptosis; cell signaling; cancer biology. Credit not granted for both MBIOS 401 and MBIOS 501. Recommended preparation for graduate students: Introductory genetics and biochemistry coursework. Offered at 400 and 500 level. Typically offered Fall, Spring, and Summer.

402 [M] Genetics Laboratory 3 (1-6) Course Prerequisite: MBIOS 301; MBIOS 304. Basic principles of modern and classical genetics utilizing several species. Typically offered Spring.

404 Molecular Biology 3 Course Prerequisite: MBIOS 301; MBIOS 303; MBIOS 305 or concurrent enrollment. Introduction of prokaryotic and eukaryotic genome organization and gene expression, modern molecular techniques, experimental approaches, genome and gene function and analyses. Typically offered Fall and Summer.

405 Cell Biology of Disease 3 Course Prerequisite: MBIOS 301; MBIOS 303. Discussion of human diseases characterized by cell biological defects, using popular press and research articles as a source of information. Credit not granted for both MBIOS 405 and 505. Offered at 400 and 500 level.

410 Medical Microbiology 3 Course Prerequisite: MBIOS 305; MBIOS 404 or concurrent enrollment. Microbial pathogens and their relationship to disease. Typically offered Spring.

411 [M] Diagnostic Medical Bacteriology 3 (1-6) Course Prerequisite: MBIOS 304; MBIOS 410 or concurrent enrollment. Techniques and tests for the identification of bacteria pathogenic for humans. Typically offered Spring.

413 General Biochemistry 3 Course Prerequisite: MBIOS 303; junior standing. Structure and function of proteins, nucleic acids and biological membranes; principles of enzymology; biochemical methodology. Credit not granted for both MBIOS 413 and MBIOS 513. Recommended preparation: Introductory biochemistry coursework. Offered at 400 and 500 level. Typically offered Fall, Spring, and Summer.

414 General Biochemistry 3 Course Prerequisite: MBIOS 413. Metabolism of carbohydrates, proteins, fats, bioenergetics; photosynthesis; control of metabolic processes. Credit not granted for both MBIOS 414 and MBIOS 514. Offered at 400 and 500 level. Typically offered Spring.

423 Human Genetics 3 Course Prerequisite: MBIOS 301. Exploration of individual and population genetics leading to critical discussion of current social, medical, and scientific issues. Typically offered Spring.

426 Microbial Genetics 3 Course Prerequisite: MBIOS 301; MBIOS 303. Genetics of bacteria, bacteriophages and plasmids; regulation of gene expression; genetic manipulation of microorganisms.

430 [M] Combined Immunology and Virology Laboratory 3 (1-6) Course Prerequisite: MBIOS 304; MBIOS 305; concurrent enrollment MBIOS 440 or 442. Fundamental principles in immunology including the cultivation and characterization of viruses using laboratory techniques. Typically offered Fall.

440 Immunology 3 Course Prerequisite: MBIOS 305. Principles of basic immunology. Credit not granted for both MBIOS 440 and MBIOS 540. Recommended preparation: Introductory microbiology coursework; concurrent enrollment with MBIOS 548 highly recommended. Offered at 400 and 500 level. Typically offered Fall. Cooperative: Open to UI degree-seeking students.

442 General Virology 3 Course Prerequisite: MBIOS 301; MBIOS 303 or concurrent enrollment. The biology of bacterial, animal, and plant viruses. Credit not granted for both MBIOS 442 and MBIOS 542. Recommended preparation: Introductory genetics and biochemistry coursework; concurrent enrollment with MBIOS 548 highly recommended. Offered at 400 and 500 level. Typically offered Spring. Cooperative: Open to UI degree-seeking students.

446 Epidemiology 3 Course Prerequisite: Junior standing. Study of diseases in human populations; concepts of etiology, disease rates, susceptibility and risk factors, screening for disease, and prevention. Typically offered Spring. Cooperative: Open to UI degree-seeking students.

450 Microbial Physiology 3 Course Prerequisite: MBIOS 303; MBIOS 304; MBIOS 305. Basic microbial physiology and its relevance to the processes of applied microbiology. Credit not granted for both MBIOS 450 and 550. Recommended preparation: Introductory genetics, biochemistry or microbiology coursework. Offered at 400 and 500 level. Typically offered Spring.

454 [M] Biochemistry Laboratory 3 (1-6) Course Prerequisite: MBIOS 303; MBIOS 304. Techniques related to the structural and functional analysis of macromolecules including proteins, lipids and carbohydrates. Typically offered Fall.

465 Principles of Biophysical Chemistry 3 Course Prerequisite: MBIOS 303; MATH 140 or 171; PHYSICS 102 or 202. Biochemical reactions and processes, molecular recognition, coupled reactions, enzyme catalysis, analysis of macromolecular structure by electrophoresis, sedimentation, viscosity, and spectroscopy. Typically offered Spring.

478 Bioinformatics 3 (2-3) Course Prerequisite: MBIOS 301, 303, or CPT S 355. Computer analysis of protein and nucleic acid sequences, functional genomics and proteomics data; modeling biological networks and pathways. Credit not granted for both MBIOS 478 and MBIOS 578. Recommended preparation: Introductory genetics or biochemistry coursework. Offered at 400 and 500 level. Typically offered Fall, Spring, and Summer.

490 Special Topics in Molecular Biology V 1-2 May be repeated for credit; cumulative maximum 6 hours. Current topics discussed by experts in the field. Typically offered Spring.

494 [CAPS] [M] Senior Project in Molecular Biosciences 3 Course Prerequisite: Certified major in Biochemistry, Genetics and Cell Biology, or Microbiology; senior standing. Written paper and seminar presentation on laboratory research project. Typically offered Fall and Spring.

495 Internship Training V 1-4 May be repeated for credit; cumulative maximum 8 hours. Course Prerequisite: By permission only. Experience in work related to specific career interests. Typically offered Fall, Spring, and Summer. S, F grading.

498 Directed Research V 1-4 May be repeated for credit. Course Prerequisite: Minimum 1 credit MBIOS 499. Continued laboratory research; requires oral or poster presentation at a WSU event or external meeting. Typically offered Fall, Spring, and Summer.

499 Special Problems V 1-4 May be repeated for credit. Independent study conducted under the jurisdiction of an approving faculty member; may include independent research studies in technical or specialized problems; selection and analysis of specified readings; development of a creative project; or field experiences. Typically offered Fall, Spring, and Summer. S, F grading.

501 Cell Biology 3 Cellular structure and function; membrane biochemistry and transport; cell-cell communication; regulation of cell cycle and apoptosis; cell signaling; cancer biology. Credit not granted for both MBIOS 401 and MBIOS 501. Recommended preparation for graduate students: Introductory genetics and biochemistry coursework. Offered at 400 and 500 level. Typically offered Fall and Spring.

503 Advanced Molecular Biology I 3 DNA replication, gene expression and regulation, including chromatin structure, DNA repair, recombination, genomic editing, and epigenetic regulation. Typically offered Fall.

503 (Effective through Summer 2017) Advanced Molecular Biology I 3 DNA replication and recombination in prokaryotes and eukaryotes; recombinant DNA methods and host/vector systems; genome analysis; transgenic organisms. Recommended preparation: Introductory genetics and biochemistry coursework. Typically offered Fall, Spring, and Summer.

504 (Effective through Summer 2017) Advanced Molecular Biology II 3 Gene expression and regulation in prokaryotes and eukaryotes, including transcription, RNA processing, and translation; chromatin structure; DNA repair. Recommended preparation: Introductory genetics and biochemistry coursework. Typically offered Fall, Spring, and Summer.

505 Cell Biology of Disease 3 Course Prerequisite: MBIOS 301; MBIOS 303. Discussion of human diseases characterized by cell biological defects, using popular press and research articles as a source of information. Credit not granted for both MBIOS 405 and 505. Offered at 400 and 500 level.

507 (Effective through Summer 2017) Critical Analysis of Scientific Literature 2 Course Prerequisite: MBIOS 503; MBIOS 513 or concurrent enrollment. Dissection and discussion of current molecular bioscience papers to foster development of critical reading of primary literature. Typically offered Fall.

508 (Effective through Summer 2017) Quantitative Approaches in Molecular Biosciences 2 Quantitative methods and techniques using examples from the current molecular biosciences primary literature. Recommended preparation: One semester of calculus. Typically offered Even Years - Fall.

513 General Biochemistry 3 Structure and function of proteins, nucleic acids and biological membranes; principles of enzymology; biochemical methodology. Credit not granted for both MBIOS 413 and MBIOS 513. Recommended preparation: Introductory biochemistry coursework. Offered at 400 and 500 level. Typically offered Fall, Spring, and Summer.

514 General Biochemistry 3 Course Prerequisite: MBIOS 513. Metabolism of carbohydrates, proteins, fats, bioenergetics; photosynthesis; control of metabolic processes. Credit not granted for both MBIOS 414 and MBIOS 514. Offered at 400 and 500 level. Typically offered Spring.

525 Advanced Topics in Genetics V 1-3 May be repeated for credit; cumulative maximum 4 hours. Recent genetics research in selected areas. Recommended preparation: MBIOS 503 or an equivalent course providing a basic understanding of molecular biology or molecular genetics. Typically offered Spring.

528 Molecular and Cellular Reproduction 3 (2-2) State of the art concepts of the molecular, cellular, and physiological aspects of mammalian reproduction. (Crosslisted course offered as MBIOS 528, ANIM SCI 558). Typically offered Even Years - Fall. Cooperative: Open to UI degree-seeking students.

529 Selected Topics in Cell Biology V 1-3 May be repeated for credit; cumulative maximum 3 hours. Selected topics in cell biology using current literature. Recommended preparation: MBIOS 401 or an equivalent course providing a basic understanding of a typical eukaryotic cell. Typically offered Spring.

540 Immunology 3 Principles of basic immunology. Credit not granted for both MBIOS 440 and MBIOS 540. Recommended preparation: Introductory microbiology coursework; concurrent enrollment with MBIOS 548 highly recommended. Offered at 400 and 500 level. Typically offered Fall. Cooperative: Open to UI degree-seeking students.

541 Research Seminar 1 May be repeated for credit; cumulative maximum 2 hours. Literature reviews and research reports. Typically offered Fall. S, F grading.

542 General Virology 3 The biology of bacterial, animal, and plant viruses. Credit not granted for both MBIOS 442 and MBIOS 542. Recommended preparation: Introductory genetics and biochemistry coursework; concurrent enrollment with MBIOS 548 highly recommended. Offered at 400 and 500 level. Typically offered Spring. Cooperative: Open to UI degree-seeking students.

548 Selected Topics in Immunology & Virology 1 May be repeated for credit; cumulative maximum 2 hours. Selected topics in immunology and virology using the current literature. Recommended preparation: Concurrent enrollment with MBIOS 540 or 542. Typically offered Fall and Spring. Cooperative: Open to UI degree-seeking students.

549 Seminar in Immunology 1 May be repeated for credit; cumulative maximum 2 hours. Seminar series on advances in immunology. May be repeated for credit; cumulative maximum 2 hours. Recommended preparation: MBIOS 540 or concurrent enrollment. Typically offered Spring.

550 Microbial Physiology 3 Basic microbial physiology and its relevance to the processes of applied microbiology. Credit not granted for both MBIOS 450 and 550. Recommended preparation: Introductory genetics, biochemistry or microbiology coursework. Offered at 400 and 500 level. Typically offered Spring.

561 Biochemical Signaling in Plants, Animals and Microorganisms 3 Course Prerequisite: MBIOS 513. New research on intra and extra cellular biochemical signaling, including communication in plants and hormone action in animals. (Crosslisted course offered as MBIOS 561, MPS 561). Typically offered Spring.

563 Deconstruction of Research 3 Course Prerequisite: Graduate standing in a WSU biomedical based graduate program. Nature and development of scientific investigation through oral and written avenues, and methods of critical analyses applied to questions of biomedical interest. (Crosslisted course offered as NEUROSCI 563, GLANHLTH 563, MBIOS 563, VET MICR 563, VET PATH 563, VET PH 563). Typically offered Fall.

564 Topics in Biomedical Experimentation V 1-3 May be repeated for credit; cumulative maximum 6 hours. Examination of the philosophy of experimental design and practical application and analysis of various experimental approaches in biomedical research. Recommended preparation: graduate standing in a WSU biomedical-based program, and an advanced undergraduate or graduate statistics course. (Crosslisted course offered as NEUROSCI 564, GLANHLTH 564, MBIOS 564, VET MICR 564, VET PATH 564, VET PH 564). Typically offered Fall.

568 Advanced Topics in Molecular Biosciences V 1-3 May be repeated for credit. Recent research in selected areas of molecular biosciences. Typically offered Fall and Spring.

574 Protein Biotechnology 3 Biotechnology related to the isolation, modification and large scale commercial production, patenting and marketing of useful recombinant proteins and products. (Crosslisted course offered as MBIOS 574, CHE 574). Recommended preparation: MBIOS 513. Typically offered Even Years - Spring.

578 Bioinformatics 3 (2-3) Computer analysis of protein and nucleic acid sequences, functional genomics and proteomics data; modeling biological networks and pathways. Credit not granted for both MBIOS 478 and MBIOS 578. Recommended preparation: Introductory genetics or biochemistry coursework. Offered at 400 and 500 level. Typically offered Fall, Spring, and Summer.

579 Molecular Biosciences Seminar 1 May be repeated for credit; cumulative maximum 10 hours. Required of all graduate students in molecular biosciences. Typically offered Fall and Spring. S, F grading.

580 Science Information Literacy 2 Efficient methods to locate and effectively use a wide variety of information resources that will be useful in the work world. Typically offered Fall, Spring, and Summer.

583 Professional Skills Seminar 1 Covers many aspects of professionalism, including professional behavior, professional dress, and professional sensitivity in social settings. Typically offered Fall, Spring, and Summer.

584 Medical Genetics 3 The mechanisms of human heredity and how these mechanisms can influence human health. Typically offered Fall, Spring, and Summer.

585 Molecular Biotechniques 2 Background and application of classical and current techniques involved in cloning, characterization, modification, and expression of genes. Typically offered Summer Session.

586 Molecular Biotechniques Laboratory 1 (0-3) Laboratory exploration of classical and current techniques involved in cloning, characterization, modification, and expression of genes. Recommended preparation: MBIOS 585 or concurrent enrollment. Typically offered Summer Session.

593 Research Proposal 2 May be repeated for credit; cumulative maximum 4 hours. Written proposal and oral defense of research project in the area of molecular biosciences. Typically offered Fall and Spring. S, F grading.

600 Special Projects or Independent Study V 1-18 May be repeated for credit. Independent study, special projects, and/or internships. Students must have graduate degree-seeking status and should check with their major advisor before enrolling in 600 credit, which cannot be used toward the core graded credits required for a graduate degree. Typically offered Fall, Spring, and Summer. S, F grading.

700 Master's Research, Thesis, and/or Examination V 1-18 May be repeated for credit. Independent research and advanced study for students working on their master's research, thesis and/or final examination. Students must have graduate degree-seeking status and should check with their major advisor/committee chair before enrolling for 700 credit. Typically offered Fall, Spring, and Summer. S, U grading.

702 Master's Special Problems, Directed Study, and/or Examination V 1-18 May be repeated for credit. Independent research in special problems, directed study, and/or examination credit for students in a non-thesis master's degree program. Students must have graduate degree-seeking status and should check with their major advisor/committee chair before enrolling for 702 credit. Typically offered Fall, Spring, and Summer. S, U grading.

800 Doctoral Research, Dissertation, and/or Examination V 1-18 May be repeated for credit. Course Prerequisite: Admitted to the Molecular Biosciences PhD program. Independent research and advanced study for students working on their doctoral research, dissertation and/or final examination. Students must have graduate degree-seeking status and should check with their major advisor/committee chair before enrolling for 800 credit. Typically offered Fall, Spring, and Summer. S, U grading.

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